Lipotransfer by centrifugation, enriched with adipose derived stem cells, in facial rejuvenation.

Abstract

Introduction: Lipotransfer is a widely used procedure for facial and body filling. However, the biggest drawback is the reabsorption of the graft, which is why the need arises to look for alternatives that improve the survival of adipose tissue with the use of stem cells derived from it obtained by nanofat. Objective: To evaluate the results of lipotransfer by centrifugation, enriched with stem cells derived from adipose tissue, in facial rejuvenation. Materials and Methods: Descriptive, longitudinal and prospective study of a series of cases in the Plastic Surgery and Caumatology Service of the Hermanos Ameijeiras Clinical Surgical Hospital, in the period between February 2019 and February 2020. Results: The average age was over 50 years old, with a female predominance in a 3: 1 ratio. Most of the patients presented a degree of aging type II and III, with a clinical evolution of 86.11% to type II, where most of the skin lesions showed improvement after the third month, being more evident at six and twelve months. 75% of the patients had a graft survival greater than 50%. There was only one complication in the receiving area. A high level of satisfaction was achieved in the patients, and the evaluation of the final result was also good in 61.11%. Conclusions: The fat transfer by centrifugation, enriched with stem cells derived from adipose tissue, allowed a good graft survival, with good clinical improvement of the skin lesions at six and twelve months, offering satisfactory results.