Influence of the COVID-19 pandemic on the therapeutic clinical spectrum of iatrogenic allogenosis in Cuba

Abstract

Introduction: Iatrogenic allogenosis has a permanent increase despite the alerts made about its incurable prognosis. Over time, its clinical spectrum evolved along with the use of new substances and medical intrusion.

 Objective: To describe the evolution of the therapeutic clinical spectrum of Iatrogenic Allogenosis at the Ameijeiras Hospital.

 Method: Descriptive, retrospective and longitudinal study in 227 patients with iatrogenic allogenosis, treated in the plastic surgery service from July/2017 to July/2022.

 Results: The predominant age group was 19-26 years (34.8%) and 96.48% were female. The most infiltrated anatomical region was the gluteal (56.39%), the injected substance the biopolymers (49.34%) with migration in 52.42% of the sample. The main reason for consultation was deformity (54.19%), followed by discoloration (28.19%). 45.81% received medical treatment, 44.05% surgical extraction by open method, 4.41% regenerative therapy with nanofat. 100% presented late satisfactory evolution. When comparing the pre- and post-covid periods, the main differences were in the injected substance, its migration, reason for consultation, and surgical treatment. The application of oil and silicone reached 20.88%, the migration to the abdominal region and genitals increased by 19.21%, the predominant reason for consultation was the change in color (12.99%), the open surgical treatment was directed to the site of migration and regenerative therapy with nanofat increased by 5.49%.

 Conclusions: The total number of post-pandemic patients quadrupled those of the pre-covid stage with modifications in the clinical presentation and changes in treatment protocols.